Infantile acropustulosisの1例

Infantile acropustulosisの1例

慶田　朋子・川上　理子・菊池　りか

A case of infantile acropustulosis

Tomoko KEIDA, Michiko KAWAKAMI, Rika KIKUTHI

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A5-month-old female infant was referred to our hospital with a 3-month history of recurrent outbreaks of pruritic vesiculopustular eruption. The lesions were initially localized on the hand and feet, and were also seen on the trunk. Bacterial and fungal cultures from the pustular exudates were negative. Direct fresh KOH examination from the pustules did not reveal mites. A skin biopsy specimen from a pustule on the dosal foot yielded a subcorneal pustule containing a lot of neutrophils, and mild perivascular lymphocytic infiltration in the dermis. Treatment with topical steroid ointment and oral antihistamines and antibiotics showed no effect. We tried topical PUVA treatment for the lesions on the palms and soles with temporary effect in reducing pustules and pruritus, but it did not lead to complete remission.
We studied 20 cases of infantile acropustulosis reported in Japan, and we also discussed the differences between infantile acropustulosis and eosinophilic pustular folliculitis in infancy.
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Key Words：Infantile acropustulosis, PUVA 療法　topical PUVA treatment, 好酸球性膿疱性毛包炎　eosinophilic pustular folliculitis